Intermediate pilomyxoid astrocytoma and diencephalic syndrome: imaging findings

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Intermediate pilomyxoid astrocytoma and diencephalic syndrome: imaging findings.

Pilomyxoid astrocytoma, an entity described as a histological variant of pilocytic astrocytoma, is a rare primary tumor of the central nervous system. It is usually located in the hypothalamic-chiasmatic area, affecting children with a mean age of 10 months. It has a high rate of recurrence and cerebrospinal fluid dissemination, which may be present throughout the neuroaxis. Due to its topograp...

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Pilomyxoid astrocytoma presenting as diencephalic syndrome.

We report the case of a child who presented with diencephalic syndrome. During diagnostic work- up, he was found to have a supra-sellar hypothalamic tumour. Histopathological examination of the tumour revealed it to be pilomyxoid astrocytoma, which is a WHO grade-II tumour, previously considered to be part of the spectrum of WHO grade-I pilocytic astrocytomas. However, because of its characteri...

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Diencephalic juvenile pilomyxoid astrocytoma with leptomeningeal dissemination.

Pilomyxoid astrocytoma (PMA) is a recently described neoplasm. PMA shares few features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays histological differences. Previous studies have shown that PMAs have more aggressive biological behavior as compared to PA. These findings suggest that PMA may be a unique and distinct...

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Diencephalic syndrome: clinical features and imaging findings.

PURPOSE To emphasize the importance of imaging in children with diencephalic syndrome due to hypothalamic/chiasmatic astrocytomas. METHODS Findings in nine patients (mean age, 26 months) with diencephalic syndrome and hypothalamic/chiasmatic astrocytomas were analyzed retrospectively, including reviewing clinical records, imaging examinations, and follow-up studies. RESULTS Symptoms and sig...

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Pilomyxoid astrocytoma: expanding the imaging spectrum.

BACKGROUND AND PURPOSE Pilomyxoid astrocytoma (PMA) is a recently described variant of pilocytic astrocytoma (PA) with unique clinical and histopathologic characteristics. Because the histopathology of PMA is distinct from that of PA, we hypothesized that PMAs would display distinctive imaging characteristics. We retrospectively reviewed the imaging findings in a large number of patients with P...

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ژورنال

عنوان ژورنال: Einstein (São Paulo)

سال: 2012

ISSN: 1679-4508

DOI: 10.1590/s1679-45082012000200020